The majority of women with scleroderma will have normal fertility. Young women with scleroderma may have a higher risk of infertility than older women who have had previous children (Lambe et al 2004).
Can scleroderma cause miscarriages?
Scleroderma appears to have little effect on fertility. There does appear to be an increased frequency of premature deliveries and lower weight infants as compared to the normal population. Miscarriage risk in scleroderma appears to be associated with the presence of antiphospholipid antibodies (APS).
Can someone with scleroderma have a baby?
For most women with scleroderma a healthy delivery and baby is possible. Disease activity: If you notice worsening of symptoms, contact your rheumatologist, because some women experience increased disease activity after delivery.
How long do you live with scleroderma?
People who have localized scleroderma may live an uninterrupted life with only minor symptom experiences and management. On the other hand, those diagnosed with an advanced and systemic version of the disease have a prognosis of anywhere from three to 15 years.
How does scleroderma affect the reproductive system?
Some evidence also exists that prior to disease onset, scleroderma patients have higher rates of infertility and delays in conception. Silman and Black (6) found a tripled rate of fertility problems before diagnosis among women with scleroderma compared with healthy controls.
What triggers scleroderma?
Research suggests that, in some people, scleroderma symptoms may be triggered by exposure to certain viruses, medications or drugs. Repeated exposure, such as at work, to certain harmful substances or chemicals also may increase the risk of scleroderma.
Does Raynaud’s get worse with pregnancy?
CONCLUSION: Patients with Raynaud’s phenomenon appear to be at increased risk for vascular complications during pregnancy such as hypertensive disorders, emergent deliveries, and poor neonatal outcomes. Obstetric providers should be aware of their increased risk and manage pregnancies accordingly.
How common is localized scleroderma?
EPIDEMIOLOGY. Localized scleroderma is more frequent than systemic scleroderma but still a rare condition. In the general populcition where systemic disease is estimated to have an incidence of 0.45 to 1.9 cases per 100,000,33,34 the incidence of the localized sclerodermas is 2.7 cases per 100,000.
How do you get systemic sclerosis?
The exact, underlying cause of systemic sclerosis is unknown. The cause appears to involve some injury to the cells that line blood vessels, resulting in excessive activation of dermal connective tissue cells, called fibroblasts . Fibroblasts normally produce collagen and other proteins .
What does crest syndrome mean?
CREST (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) syndrome is a member of the heterogeneous group of sclerodermas, and its name is an acronym for the cardinal clinical features of the syndrome.
Is scleroderma a death sentence?
With proper management and constant consultation, patients with scleroderma would live to the fullest, a professor of medicine and consultant rheumatologist at Lagos State University Teaching Hospital (LASUTH), Femi Adelowo has said.
What should I avoid with scleroderma?
REFLUX/HEARTBURN: eat small frequent meals to avoid overfilling your stomach; avoid eating within 2-3 hours of bedtime; avoid foods that may aggravate symptoms such as citrus fruits, tomato products, greasy fried foods, coffee, garlic, onions, peppermint, gas-producing foods (such as raw peppers, beans, broccoli, raw …
Can scleroderma be reversed?
There is no cure for scleroderma. Medications can treat symptoms and prevent complications. Making changes to your lifestyle and diet can make living with the disease easier.
How does scleroderma affect vagina?
Vaginal dryness. ‘Sjögrens syndrome’ or ‘sicca syndrome’ often accompanies systemic sclerosis. This causes dryness of the mucous membranes, typically leading to dry eyes and a dry mouth. The vagina can also be affected, and with less lubrication during arousal, sex can be uncomfortable, or even painful.
The coexistence of lichen sclerosus and scleroderma plaques in most cases with extragenital location has been reported in the literature. We report a case of lichen sclerosus associated with scleroderma in children, highlighting the importance of dermoscopy in diagnosis.
Does Morphea affect pregnancy?
Thus pregnancy might be a predisposing factor of morphea because of the microchimerism. Indeed, chimeric cells are none self-cells transferred from fetus to mother during pregnancy. In addition, the pregnancy can alter the disease course of autoimmune diseases, including localized scleroderma.